Polynucleotides vs. Skin Boosters - find out which one is best for you

Polynucleotides vs. Skin Boosters: What's the Difference and Which Is Right for You?

Polynucleotide & Skin Boosters available at Renew & Revive, Prudhoe, Newcastle

If you're on a journey to fresher, firmer, and more radiant skin, chances are you've come across terms like skin boosters and polynucleotides. They both promise smoother, hydrated skin—but they work in very different ways.

So, how do you know which one is right for you?

Let’s break it down.

What Are Skin Boosters?

Skin boosters are injectable treatments designed to hydrate the skin and improve its texture and elasticity deeply. The most common ingredient in skin boosters is hyaluronic acid (HA), a naturally occurring substance in the skin that attracts and holds water.

Skin Boosters are perfect for:

Long-lasting hydration,

A dewy, plump appearance,

Improved skin elasticity,

A subtle glow without adding volume

Skin boosters are excellent for individuals with dry, dull, or crepey skin—especially in areas such as the face, neck, décolleté, and hands.

What Are Polynucleotides?

Polynucleotides (PNs) are regenerative biostimulators. Rather than hydrating from the outside, they work deeper within the skin’s cellular structure, encouraging tissue repair, collagen production, and anti-inflammatory responses.

Derived from purified DNA fragments (usually from salmon), polynucleotides:

They provide: Promote cell renewal,

Improve skin texture and tone,

Reduce inflammation and pigmentation,

Stimulate fibroblast activity (which boosts collagen and elastin),

Support skin healing and regeneration over time

Think of them as “cell whisperers”—coaching your skin to restore itself, rather than simply topping it up with hydration.

Head-to-Head: Key Differences

Feature	Skin Boosters	Polynucleotides
Main Action	Deep hydration	Skin regeneration & repair
Primary Ingredient	Hyaluronic acid	DNA fragments (usually from salmon)
Speed of Results	Quick glow (1–2 weeks)	Gradual improvement (4–6 weeks)
Best For	Dehydrated, dull skin	Tired, thin, damaged or aging skin
Treatment Areas	Face, neck, chest, hands	Under eyes, face, neck, scars
Duration of Results	6 months	6 months
Number of Sessions	Usually 2–3	Usually 3

Which One Should You Choose?

💧 Choose Skin Boosters if: You want quick hydration and a glow-up, have dull or crepey skin, or need a boost before an event. Skin boosters provide the “glass skin” finish that’s ideal for tired or dehydrated complexions.

🧬 Choose Polynucleotides if: You’re noticing early signs of aging, inflammation, or pigmentation or if you want to strengthen and rejuvenate your skin from within over time. They’re ideal for under-eye areas, post-acne scars, or skin that’s lost its natural vitality.

✅ Pro Tip: Many clinics combine both treatments for a layered, synergistic approach—hydration from skin boosters + regeneration from polynucleotides.

Final Thoughts

Both skin boosters and polynucleotides have their place in modern aesthetics, but the right one for you depends on your goals. Whether you're after instant dewiness or long-term skin healing, there's a tailored solution waiting.

Ready to glow from the inside out? Book a consultation to determine which treatment is best suited for your skin’s specific needs .

Book here